Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Ohio State University, Wexner Medical Center, Columbus, OH, USA.
Int J Chron Obstruct Pulmon Dis. 2014 Apr 8;9:349-62. doi: 10.2147/COPD.S42394. eCollection 2014.
Chronic obstructive pulmonary disease (COPD) is a common and preventable lung disease that affects millions of people in the United States. Sleep disorders including obstructive sleep apnea (OSA) are also common. It is not surprising that many people with COPD also suffer from OSA. This relationship, however, puts people at risk for more nocturnal desaturations and potential complications related to this, including pulmonary hypertension and heart rhythm disturbances. This update focuses on the physiology of sleep disturbances in COPD as well as the clinical implications of OSA in COPD.
慢性阻塞性肺疾病（COPD）是一种常见且可预防的肺部疾病，影响着美国数以百万计的人。睡眠障碍，包括阻塞性睡眠呼吸暂停（OSA），也很常见。因此，许多 COPD 患者也患有 OSA 并不奇怪。然而，这种关系使人们面临更多夜间低氧血症和与低氧血症相关的潜在并发症的风险，包括肺动脉高压和心律紊乱。本更新重点介绍 COPD 中睡眠障碍的生理学以及 COPD 中 OSA 的临床意义。
