Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland.
University Hospital Vall d'Hebron, Ciberehd, Barcelona 08035, Spain.
Nat Rev Gastroenterol Hepatol. 2014 Aug;11(8):506-14. doi: 10.1038/nrgastro.2014.66. Epub 2014 Jun 10.
An expert panel was convened in October 2013 by the International Scientific Association for Probiotics and Prebiotics (ISAPP) to discuss the field of probiotics. It is now 13 years since the definition of probiotics and 12 years after guidelines were published for regulators, scientists and industry by the Food and Agriculture Organization of the United Nations and the WHO (FAO/WHO). The FAO/WHO definition of a probiotic--"live microorganisms which when administered in adequate amounts confer a health benefit on the host"--was reinforced as relevant and sufficiently accommodating for current and anticipated applications. However, inconsistencies between the FAO/WHO Expert Consultation Report and the FAO/WHO Guidelines were clarified to take into account advances in science and applications. A more precise use of the term 'probiotic' will be useful to guide clinicians and consumers in differentiating the diverse products on the market. This document represents the conclusions of the ISAPP consensus meeting on the appropriate use and scope of the term probiotic.
一个专家小组于 2013 年 10 月由国际益生菌和益生元科学协会（ISAPP）召集，讨论益生菌领域的问题。自益生菌的定义提出以来已经过去了 13 年，自联合国粮食及农业组织和世界卫生组织（FAO/WHO）为监管机构、科学家和行业发布指南以来也已经过去了 12 年。FAO/WHO 对益生菌的定义是：“当以足够的数量施用时，赋予宿主健康益处的活微生物”，这一定义被认为与当前和预期的应用相关，并且具有足够的适应性。然而，为了考虑到科学和应用的进步，已经澄清了 FAO/WHO 专家磋商报告与 FAO/WHO 指南之间的不一致之处。更准确地使用“益生菌”一词将有助于指导临床医生和消费者区分市场上的各种产品。本文件代表了 ISAPP 关于益生菌一词的适当使用和范围的共识会议的结论。
