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Flap endonuclease 1: a novel tumour suppresser protein.

作者信息

Henneke Ghislaine, Friedrich-Heineken Erica, Hübscher Ulrich

机构信息

Institute of Veterinary Biochemistry and Molecular Biology, University of Zürich-Irchel, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.

出版信息

Trends Biochem Sci. 2003 Jul;28(7):384-90. doi: 10.1016/S0968-0004(03)00138-5.

DOI:10.1016/S0968-0004(03)00138-5
PMID:12878006
Abstract
摘要

相似文献

1
Flap endonuclease 1: a novel tumour suppresser protein.瓣内切核酸酶1：一种新型肿瘤抑制蛋白。
Trends Biochem Sci. 2003 Jul;28(7):384-90. doi: 10.1016/S0968-0004(03)00138-5.
2
The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.人类FEN1核酸内切酶的柔性环在DNA复制和修复过程中的瓣状切割中是必需的。
EMBO J. 2002 Nov 1;21(21):5930-42. doi: 10.1093/emboj/cdf587.
3
Human flap endonuclease-1: conformational change upon binding to the flap DNA substrate and location of the Mg2+ binding site.人瓣内切核酸酶-1：与瓣状DNA底物结合后的构象变化及Mg2+结合位点的定位
Biochemistry. 2001 Mar 13;40(10):3208-14. doi: 10.1021/bi002100n.
4
Flap endonuclease 1 efficiently cleaves base excision repair and DNA replication intermediates assembled into nucleosomes.瓣内切核酸酶1能有效切割组装成核小体的碱基切除修复和DNA复制中间体。
Mol Cell. 2002 Nov;10(5):1201-11. doi: 10.1016/s1097-2765(02)00736-0.
5
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii.詹氏甲烷球菌中瓣状核酸内切酶-1的晶体结构。
Nat Struct Biol. 1998 Aug;5(8):707-13. doi: 10.1038/1406.
6
Thermostable flap endonuclease from the archaeon, Pyrococcus horikoshii, cleaves the replication fork-like structure endo/exonucleolytically.来自古菌嗜热栖热菌的热稳定瓣状核酸内切酶以内切/外切方式切割复制叉样结构。
J Biol Chem. 1999 Jun 25;274(26):18297-309. doi: 10.1074/jbc.274.26.18297.
7
Arginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determination.人瓣内切核酸酶-1的精氨酸残基47和70参与DNA底物相互作用和切割位点的确定。
J Biol Chem. 2002 Jul 5;277(27):24659-66. doi: 10.1074/jbc.M111941200. Epub 2002 May 1.
8
Mutator specificity and disease: looking over the FENce.突变特异性与疾病：审视FENce
Cell. 1997 Jan 24;88(2):155-8. doi: 10.1016/s0092-8674(00)81832-2.
9
Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity.DNA修复与复制内切核酸酶和外切核酸酶FEN-1的结构：DNA与增殖细胞核抗原（PCNA）结合与FEN-1活性的偶联
Cell. 1998 Oct 2;95(1):135-46. doi: 10.1016/s0092-8674(00)81789-4.
10
[Interaction of replication protein A and flap endonuclease 1 with DNA duplexes containing a nick or flap].复制蛋白A与瓣状核酸内切酶1与含切口或瓣状结构的DNA双链体的相互作用
Mol Biol (Mosk). 2002 Nov-Dec;36(6):1044-53.

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2005年至2019年 flap内切核酸酶1研究的文献计量分析
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Impact of Infection and Its Major Virulence Factor CagA on DNA Damage Repair.感染及其主要毒力因子CagA对DNA损伤修复的影响。
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TGFβ1- miR-140-5p axis mediated up-regulation of Flap Endonuclease 1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma.转化生长因子β1-微小RNA-140-5p轴介导的瓣内切酶1上调促进肝细胞癌上皮-间质转化
Aging (Albany NY). 2019 Aug 10;11(15):5593-5612. doi: 10.18632/aging.102140.
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Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus.Flap endonuclease 1 参与乙型肝炎病毒 cccDNA 的形成。
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Flap endonuclease-1 rs174538 G>A polymorphisms are associated with the risk of esophageal cancer in a Chinese population.Flap endonuclease-1 rs174538 G>A 多态性与中国人群食管癌风险相关。
Thorac Cancer. 2017 May;8(3):192-196. doi: 10.1111/1759-7714.12422. Epub 2017 Mar 20.
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Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1.单分子荧光共振能量转移揭示了瓣状核酸内切酶1底物选择性的诱导契合机制。
Elife. 2017 Feb 23;6:e21884. doi: 10.7554/eLife.21884.
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FEN1 gene variants confer reduced risk of breast cancer in chinese women: A case-control study.FEN1基因变异降低中国女性患乳腺癌风险：一项病例对照研究。
Oncotarget. 2016 Nov 22;7(47):78110-78118. doi: 10.18632/oncotarget.12948.
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Requirement for flap endonuclease 1 (FEN1) to maintain genomic stability and transcriptional gene silencing in Arabidopsis.拟南芥中瓣状核酸内切酶1（FEN1）对维持基因组稳定性和转录基因沉默的需求。
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