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原发性高血压患者降低血压需要多少运动量:一项剂量反应研究。

How much exercise is required to reduce blood pressure in essential hypertensives: a dose-response study.

作者信息

Ishikawa-Takata Kazuko, Ohta Toshiki, Tanaka Hirofumi

机构信息

Division of Health Promotion and Exercise (KI-T), National Institute of Health and Nutrition, 1-23-1 Toyama Shinjyuku, Tokyo 162-8636, Japan.

出版信息

Am J Hypertens. 2003 Aug;16(8):629-33. doi: 10.1016/s0895-7061(03)00895-1.

DOI:10.1016/s0895-7061(03)00895-1
PMID:12878367
Abstract

BACKGROUND

Regular aerobic exercise is widely recommended for essential hypertensives. However, it is not clear how much exercise is needed to reduce blood pressure (BP).

METHODS

The dose-response relation of exercise training and BP was determined using an 8-week exercise intervention study involving 207 untreated subjects with stage 1 or 2 essential hypertension. Subjects were divided into five groups based on the duration and frequency/week of exercise (sedentary control, 30 to 60 min/wk, 61 to 90 min/wk, 91 to 120 min/wk, and >120 min/wk). Age, gender, height, body mass, body mass index, dietary intake, and baseline BP were not different among the groups.

RESULTS

Both systolic and diastolic BP at rest did not change in the nonexercising control group. All four exercise groups demonstrated significant reductions in both systolic and diastolic BP at rest. The magnitude of reductions in systolic BP was greater in the 61 to 90 min/wk group compared with the 30 to 60 min/wk group. There were no greater reductions in systolic BP with further increases in exercise volume. The magnitude of reductions in diastolic BP was not significantly different among four exercise groups. There were no obvious relations between exercise frequency per week and the magnitude of BP decreases with exercise training.

CONCLUSIONS

In previously sedentary hypertensive subjects, clinically significant decreases in BP can be achieved with relatively modest increases in physical activity above sedentary levels and that the volume of exercise required to reduce BP may be relatively small that should be reasonably attainable by a sedentary hypertensive population.

摘要

背景

对于原发性高血压患者,普遍建议进行规律的有氧运动。然而,尚不清楚需要多少运动量才能降低血压(BP)。

方法

通过一项为期8周的运动干预研究来确定运动训练与血压之间的剂量反应关系,该研究纳入了207名未经治疗的1或2期原发性高血压患者。根据运动持续时间和每周运动频率,将受试者分为五组(久坐对照组、每周30至60分钟、每周61至90分钟、每周91至120分钟以及每周超过120分钟)。各组之间的年龄、性别、身高、体重、体重指数、饮食摄入量和基线血压并无差异。

结果

非运动对照组静息时的收缩压和舒张压均未发生变化。所有四个运动组静息时的收缩压和舒张压均显著降低。与每周30至60分钟组相比,每周61至90分钟组的收缩压降低幅度更大。随着运动量进一步增加,收缩压降低幅度并未进一步增大。四个运动组之间舒张压降低幅度无显著差异。每周运动频率与运动训练导致的血压降低幅度之间无明显关系。

结论

在既往久坐不动的高血压患者中,相较于久坐水平,适度增加体力活动即可实现临床上显著的血压降低,且降低血压所需的运动量可能相对较小,久坐的高血压人群应该能够合理达到这一运动量。

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