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精神科门诊及住院患者中重度抑郁症的DSM-IV标准自我评估

Self-assessment of DSM-IV criteria for major depression in psychiatric out- and inpatients.

作者信息

Svanborg Pär, Ekselius Lisa

机构信息

Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institute, Stockholm, Sweden.

出版信息

Nord J Psychiatry. 2003;57(4):291-6. doi: 10.1080/08039480307281.

DOI:10.1080/08039480307281
PMID:12888397
Abstract

The Depression Self-Rating Scale (DSRS) is a self-report inventory based on the DSM-IV criteria for major depression. This study aimed to investigate diagnostic concordance of a major depressive disorder (MDD) using the DSRS and the Structured Clinical Interview for DSM-IV, axis I disorders (SCID-I). An additional aim was to investigate whether concordance could be improved by adding different cut-off scores for the Beck Depression Inventory (BDI) or the self-report version of the Montgomery-Asberg Depression Rating Scale (MADRS-S). MDD was determined by means of the SCID-I interview and the DSRS in 83 psychiatric in- and outpatients. Depressive severity was assessed using the BDI and the MADRS-S. A DSRS-version including the A- and C-criteria for an MDD had a sensitivity and a specificity for an expert-rated diagnosis of 86% and 75%, respectively. By using cut-off scores for the BDI or the MADRS-S, specificity could be raised to 85% without loss of sensitivity. The DSRS appears to be a useful instrument in the diagnostic process involving MDD, particularly when used in combination with the BDI or the MADRS-S. The DSRS is thought to be of value in psychiatric outpatient departments, where treatment of patients is often delegated to paramedical staff or nurses. The scale might also be used as an independent diagnostic tool in epidemiological studies in order to achieve an estimate of the prevalence of MDD in different population settings.

摘要

抑郁自评量表(DSRS)是一种基于《精神疾病诊断与统计手册第四版》(DSM-IV)中重度抑郁症标准的自我报告量表。本研究旨在调查使用DSRS和《DSM-IV轴I障碍结构化临床访谈》(SCID-I)诊断重度抑郁症(MDD)的一致性。另一个目的是研究通过为贝克抑郁量表(BDI)或蒙哥马利-阿斯伯格抑郁评定量表自我报告版(MADRS-S)添加不同的临界值分数,是否可以提高一致性。通过SCID-I访谈和DSRS对83名精神科门诊和住院患者进行MDD诊断。使用BDI和MADRS-S评估抑郁严重程度。包含MDD的A和C标准的DSRS版本对专家评定诊断的敏感性和特异性分别为86%和75%。通过使用BDI或MADRS-S的临界值分数,特异性可提高到85%而不损失敏感性。DSRS似乎是MDD诊断过程中的一种有用工具,特别是与BDI或MADRS-S联合使用时。DSRS被认为在精神科门诊有价值作用,在那里患者的治疗通常委托给辅助医务人员或护士。该量表也可作为流行病学研究中的独立诊断工具,以便估计不同人群中MDD的患病率。

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