细胞周期特异性高尔基体断裂：方式与原因？

Cell-cycle-specific Golgi fragmentation: how and why?

作者信息

Colanzi Antonino, Suetterlin Christine, Malhotra Vivek

机构信息

Cell and Developmental Biology, University of California San Diego, La Jolla, CA 92093, USA.

出版信息

Curr Opin Cell Biol. 2003 Aug;15(4):462-7. doi: 10.1016/s0955-0674(03)00067-x.

DOI:10.1016/s0955-0674(03)00067-x

PMID:12892787

Abstract

The Golgi membranes, in the form of stacks of cisternae, are contained in the pericentriolar region of mammalian cells. During mitosis, these membranes are fragmented and dispersed throughout the cell. Recent studies are revealing the significance of pericentriolar position of the Golgi apparatus and mechanism by which these membranes are fragmented during mitosis.

摘要

呈扁平囊堆叠形式的高尔基体膜存在于哺乳动物细胞的中心粒周围区域。在有丝分裂期间，这些膜会破碎并分散于整个细胞中。最近的研究正在揭示高尔基体中心粒周围位置的重要性以及这些膜在有丝分裂期间破碎的机制。