Beaton Dorcas E, Schemitsch Emil
Mobility Program Clinical Research Unit and the Martin Family Centre for Arthritis Care and Research, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario M5B 1W8, Canada.
Clin Orthop Relat Res. 2003 Aug(413):90-105. doi: 10.1097/01.blo.0000079772.06654.c8.
Outcome measures may be seen as windows, each of which provides a different perspective on a single view, the impact of a disease or disorder on the patient concerned. A comparison of the orthopaedic literature in 1991 with that in 2001 suggests that the intervening decade saw an increasing interest in the use of patient-based measures in clinical outcome studies, particularly randomized controlled trials. The tool most commonly used to determine the patient's point of view was the generic Short Form-36 (SF-36). Other measures included regional assessments such as the Musculoskeletal Functional Assessment, or the Disability of the Arm, Shoulder and Hand. The Western Ontario McMaster Osteoarthritis Index (WOMAC) (hip and knee), the Simple Shoulder Test (shoulder) and the Roland-Morris Questionnaire or Oswestry Disability Index (low back) were the most common joint-specific measures. Each of the questionnaires reported was supported by evidence of reliability and validity, and in most cases one or more studies had shown responsiveness in at least musculoskeletal disorders. We provide a brief description of the most common tools, and review the evidence that orthopaedic research is making increased use of measures of health status and function.
结果指标可被视为窗口，每个窗口都能从单一视角——疾病或紊乱对相关患者的影响，提供不同的观点。将1991年与2001年的骨科文献进行比较表明，在这十年间，临床结局研究中对基于患者的指标的使用兴趣日益增加，尤其是在随机对照试验中。最常用于确定患者观点的工具是通用的简短健康调查问卷（SF - 36）。其他指标包括局部评估，如肌肉骨骼功能评估，或上肢、肩部和手部功能障碍评估。西安大略和麦克马斯特大学骨关节炎指数（WOMAC）（髋部和膝部）、简易肩部测试（肩部）以及罗兰 - 莫里斯问卷或奥斯威斯垂残疾指数（下背部）是最常见的特定关节指标。所报告的每份问卷都有可靠性和有效性的证据支持，并且在大多数情况下，有一项或多项研究表明这些问卷至少在肌肉骨骼疾病方面具有反应性。我们简要描述了最常用的工具，并回顾了骨科研究越来越多地使用健康状况和功能指标的证据。
