Yasuhara Daisuke, Deguchi Daisuke, Tsutsui Junko, Nagai Nobuatsu, Nozoe Shin-ichi, Naruo Tetsuro
Department of Psychosomatic Medicine, Kagoshima University Hospital, Kagoshima-city, Japan.
Int J Eat Disord. 2003 Sep;34(2):273-7. doi: 10.1002/eat.10182.
The relationship among reactive hypoglycemia, corresponding insulin metabolism, and eating behavior in anorexia nervosa (AN) has not been well documented.
A 22-year-old woman with AN was admitted to Kagoshima University Hospital. An oral glucose tolerance test was performed with additional sampling at 15 minutes on the seventh hospital day when her daily caloric intake rapidly increased, reaching 2,000kcal perday.
An elevated level of insulin secretion (1,190pmol/L) was observed during the very early phase (15 minutes) after glucose load, whereas corresponding blood glucose elevations were not as high (1.2mmol/L). The patient experienced asymptomatic hypoglycemia (2.1mmol/L).
Our findings suggested that a rapid increase of energy intake might cause reactive hypoglycemia with characteristic insulin metabolism, that is, an elevated level of insulin secretion during the very early phase.
