Baldi J C, Snowling N
The University of Auckland, Department of Sport and Exercise Science, Auckland, New Zealand.
Int J Sports Med. 2003 Aug;24(6):419-23. doi: 10.1055/s-2003-41173.
The purpose of this investigation was to determine whether moderate intensity resistance training (RT) improves glycaemic control in obese, type 2 diabetic men. Eighteen subjects were randomly assigned to a 10-week RT program, or a non-training control group (C). Glycosylated haemoglobin (HbA 1c ), fasting glucose and insulin, glucose and insulin 120 minutes (2h) after a 75 g oral glucose load, body composition and muscular strength and endurance were measured before and after the 10-week experimental period. In the RT group fasting glucose and insulin decreased with training (p < 0.05) and decreases in HbA 1c approached significance (p = 0.057). 2-h glucose and insulin did not change in either group. Fat free mass (FFM) increased by 3.5 % after RT but was unchanged in the controls. Fat mass (FM) increased 6.9 % in C but was unchanged in RT. Percent body fat was unchanged in both groups. Muscular strength and endurance increased by 25 to 52 % in the RT group but was unchanged in controls. Changes in fasting glucose and HbA 1c were inversely related to changes in FFM. These results suggest that RT is an effective form of exercise training which modestly improves glycaemic control and lowers fasting insulin levels in obese type 2 diabetics.
本研究的目的是确定中等强度抗阻训练(RT)是否能改善肥胖2型糖尿病男性的血糖控制。18名受试者被随机分为10周抗阻训练组或非训练对照组(C)。在10周实验期前后,测量糖化血红蛋白(HbA 1c)、空腹血糖和胰岛素、75克口服葡萄糖负荷后120分钟(2小时)的血糖和胰岛素、身体成分以及肌肉力量和耐力。在抗阻训练组中,空腹血糖和胰岛素随训练降低(p < 0.05),HbA 1c的降低接近显著水平(p = 0.057)。两组的2小时血糖和胰岛素均未改变。抗阻训练后去脂体重(FFM)增加了3.5%,但对照组未改变。对照组的脂肪量(FM)增加了6.9%,但抗阻训练组未改变。两组的体脂百分比均未改变。抗阻训练组的肌肉力量和耐力增加了25%至52%,但对照组未改变。空腹血糖和HbA 1c的变化与FFM的变化呈负相关。这些结果表明,抗阻训练是一种有效的运动训练形式,可适度改善肥胖2型糖尿病患者的血糖控制并降低空腹胰岛素水平。