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[评估结核病变活动度的免疫学方法]

[Immunological approach to the evaluation of the activity of the tuberculous process].

作者信息

Kwiatkowska S, Rozniecki J

机构信息

Kliniki Pneumonologii i Alergologii IMW AM, Lodzi.

出版信息

Pneumonol Alergol Pol. 1992;60(5-6):18-25.

PMID:1290985
Abstract

The aim of the study was to determine the immunological criteria of the activity of the lung tuberculosis. Some immunological tests based on cellular and humoral immunity were assessed in 3 groups: I--patients with active, bacteriologically confirmed tuberculosis, II--individuals with inactive minimal changes in the lung, III--healthy subjects. We found that among patients with active tuberculosis cellular immunity was depressed: both percentage of T-lymphocytes and their function, usually associated with cutaneous anergy to tuberculin. But the humoral immunity was enhanced. The authors have shown that the people with inactive minimal changes in the lung take place between the patients with active tuberculosis and healthy subjects.

摘要

该研究的目的是确定肺结核活动的免疫学标准。基于细胞免疫和体液免疫的一些免疫学检测在3组人群中进行了评估:I组——痰菌阳性的活动性肺结核患者;II组——肺部有非活动性微小病变的个体;III组——健康受试者。我们发现,活动性肺结核患者的细胞免疫受到抑制:T淋巴细胞的百分比及其功能均下降,这通常与对结核菌素的皮肤无反应性相关。但体液免疫增强。作者表明,肺部有非活动性微小病变的人群处于活动性肺结核患者和健康受试者之间。

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