Ikoona Erick, Kalyesubula Israel, Kawuma Medi
Department of Ophthalmology, Makerere University, Kampala, Uganda.
Afr Health Sci. 2003 Aug;3(2):83-6.
In Uganda the prevalence of HIV averages 12% as was reported to the STD/AIDS control surveillance unit. In Uganda there are approximately 30,000 HIV infected infants per year. The burden of HIV disease is high in Uganda and patients present with ocular complications. However, there is paucity of information and knowledge concerning ocular manifestations in the paediatric HIV/AIDS population and how they may differ from those of adults.
To describe the ocular manifestations of HIV/AIDS infection in an African paediatric population. Generally the study will record the external ocular manifestations seen but specifically to document the intra-ocular lesions, in particular the retinal changes associated with paediatric HIV/AIDS.
A cross-sectional hospital based study.
The study was conducted at the Paediatric Infectious Disease Clinic at Upper Mulago Hospital, in Kampala, Uganda.
Patients are those with positive HIV sero status, with or without symptoms and signs of AIDS. Parents/caretakers of the children were interviewed to obtain the socio-demographic data of the patients and a general physical as well as an ophthalmic examination were conducted to document any ocular problems.
A total of 158 HIV -infected children were examined. The overall rate of ophthalmic involvement was 35%. The most common finding was a non-purulent conjuctivitis, observed in 12% of the patients, followed by perivasculitis of the peripheral retinal vessels, in 12% of patients and molluscum contagiosum.
据乌干达性传播疾病/艾滋病控制监测部门报告，该国艾滋病病毒（HIV）感染率平均为12%。乌干达每年约有30000名感染HIV的婴儿。乌干达的HIV疾病负担很高，患者会出现眼部并发症。然而，关于儿科HIV/AIDS人群的眼部表现以及这些表现与成人有何不同的信息和知识却很匮乏。
描述非洲儿科人群中HIV/AIDS感染的眼部表现。总体而言，该研究将记录所观察到的外部眼部表现，但具体是为了记录眼内病变，特别是与儿科HIV/AIDS相关的视网膜变化。
一项基于医院的横断面研究。
该研究在乌干达坎帕拉市上穆拉戈医院的儿科传染病诊所进行。
HIV血清学检测呈阳性的患者，无论有无艾滋病症状和体征。对儿童的父母/照料者进行访谈以获取患者的社会人口学数据，并进行全面体格检查和眼科检查，以记录任何眼部问题。
共检查了158名感染HIV的儿童。眼科受累的总体发生率为35%。最常见的发现是12%的患者出现非脓性结膜炎，其次是12%的患者出现周边视网膜血管的血管周炎和传染性软疣。
