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天花疫苗接种政策中的群体利益与个人利益

Group interest versus self-interest in smallpox vaccination policy.

作者信息

Bauch Chris T, Galvani Alison P, Earn David J D

机构信息

Department of Mathematics and Statistics, McMaster University, Hamilton, ON, Canada L8S 4K1.

出版信息

Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10564-7. doi: 10.1073/pnas.1731324100. Epub 2003 Aug 14.

Abstract

The recent threat of bioterrorism has fueled debate on smallpox vaccination policy for the United States. Certain policy proposals call for voluntary mass vaccination; however, if individuals decide whether to vaccinate according to self-interest, the level of herd immunity achieved may differ from what is best for the population as a whole. We present a synthesis of game theory and epidemic modeling that formalizes this conflict between self-interest and group interest and shows that voluntary vaccination is unlikely to reach the group-optimal level. This shortfall results in a substantial increase in expected mortality after an attack.

摘要

近期生物恐怖主义的威胁引发了美国关于天花疫苗接种政策的争论。某些政策提议呼吁进行自愿大规模接种;然而,如果个人根据自身利益决定是否接种,所实现的群体免疫水平可能与对整个人口最有利的水平有所不同。我们提出了一种博弈论与流行病建模的综合方法,将这种自身利益与群体利益之间的冲突形式化,并表明自愿接种不太可能达到群体最优水平。这种不足导致袭击后预期死亡率大幅上升。

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Group interest versus self-interest in smallpox vaccination policy.天花疫苗接种政策中的群体利益与个人利益
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本文引用的文献

1
A model for a smallpox-vaccination policy.一种天花疫苗接种政策模型。
N Engl J Med. 2003 Jan 30;348(5):416-25. doi: 10.1056/NEJMsa025075. Epub 2002 Dec 19.
3
Containing bioterrorist smallpox.含有生物恐怖主义天花病毒。
Science. 2002 Nov 15;298(5597):1428-32. doi: 10.1126/science.1074674.
4
The smallpox vaccine debate.天花疫苗辩论。
Am J Nurs. 2002 Sep;102(9):33-8; quiz 38-9. doi: 10.1097/00000446-200209000-00032.
5
Emergency response to a smallpox attack: the case for mass vaccination.针对天花袭击的应急响应:大规模接种疫苗的理由。
Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10935-40. doi: 10.1073/pnas.162282799. Epub 2002 Jul 12.
6
The case for voluntary smallpox vaccination.自愿接种天花疫苗的理由。
N Engl J Med. 2002 Apr 25;346(17):1323-5. doi: 10.1056/NEJM200204253461713. Epub 2002 Mar 28.

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