Ohberg Lars, Alfredson Håkan
Department of Radiation Sciences, Diagnostic Radiology, Umeå University, 90185, Umeå, Sweden.
Knee Surg Sports Traumatol Arthrosc. 2003 Sep;11(5):339-43. doi: 10.1007/s00167-003-0402-7. Epub 2003 Aug 19.
The origin of Achilles tendon insertional pain has not been clarified. Treatment is considered difficult, though tendon, bone, and bursae, alone or in combination, may all be the source of pain. Recently, neovascularisation in the area with tendon changes was shown to correlate with pain in patients with chronic mid-portion Achilles tendinosis. In a pilot study, sclerosing the neovessels outside the tendon cured the pain in the majority of patients. In this pilot-study, ultrasonography and colour Doppler was used for the investigation of eleven patients (nine men and two women, mean age 44 years) with a long duration (mean 29 months) of chronic Achilles tendon insertional pain. All patients had distal tendon changes and a local neovascularisation inside and outside the distal tendon on the injured/painful side, but not on the noninjured/pain-free side. In nine patients there was also a thickened retrocalcaneal bursae, and in four patients also bone pathology (calcification, spur, loose fragment) in the insertion. The sclerosing agent polidocanol was injected against the local neovessels found in all patients. At follow-up (mean eight months), sclerosing of the area with neovessels had cured the pain in eight out of eleven patients, and in seven of the eight patients there was no neovascularisation. Pain during tendon-loading activity, recorded on a VAS-scale, decreased from 82 mm before treatment to 14 mm after treatment in the successfully treated patients. In conclusion, treatment only focusing on sclerosing the area with neovessels showed promising short-term clinical results in this small pilot study. The findings support further studies, preferably in a randomised manner.
跟腱止点疼痛的病因尚未明确。尽管肌腱、骨骼和滑囊单独或共同作用都可能是疼痛的来源,但治疗仍被认为具有挑战性。最近的研究表明,慢性跟腱中部肌腱病患者中,肌腱发生改变区域的新生血管形成与疼痛相关。在一项初步研究中,对肌腱外的新生血管进行硬化治疗使大多数患者的疼痛得到缓解。在这项初步研究中,使用超声和彩色多普勒对11例(9例男性和2例女性,平均年龄44岁)患有慢性跟腱止点疼痛且病程较长(平均29个月)的患者进行了检查。所有患者在受伤/疼痛侧的跟腱远端均有改变,且远端肌腱内外均有局部新生血管形成,而在未受伤/无痛侧则没有。9例患者还伴有跟腱后滑囊增厚,4例患者在止点处还存在骨病变(钙化、骨刺、游离碎片)。向所有患者发现的局部新生血管内注射硬化剂聚多卡醇。随访(平均8个月)时,对新生血管区域进行硬化治疗使11例患者中的8例疼痛得到缓解,其中8例中的7例新生血管消失。在成功治疗的患者中,通过视觉模拟评分法记录的肌腱负荷活动时的疼痛,从治疗前的82毫米降至治疗后的14毫米。总之,在这项小型初步研究中,仅专注于对新生血管区域进行硬化治疗显示出了有前景的短期临床效果。这些发现支持进一步开展研究,最好采用随机方式。