Sauret J, Jolis R, Ausina V, Castro E, Cornudella R
Hospital de la Santa Cruz, San Pablo, Spain.
Tuber Lung Dis. 1992 Dec;73(6):388-91. doi: 10.1016/0962-8479(92)90046-M.
During the period 1986-1990, 10 cases of human disease caused by Mycobacterium bovis were diagnosed in our hospital. The incidence, in relation to the cases of disease from Mycobacterium tuberculosis diagnosed in the same period, was 0.9%. The patients had an average age of 32 years (range 5-68 years). Pulmonary disease was observed in 5 patients (50%), lymphadenitis in 2, pleural effusion in 2 and peritoneal in 1. The most significant of the epidemiological features was that 2 patients were veterinary students. There was 1 death from ovarian neoplasia with abdominal dissemination. The other cases responded favourably to treatment with standard chemotherapy of 6-12 months achieving cure, without relapse, of all the patients.
1986年至1990年期间,我院诊断出10例由牛分枝杆菌引起的人类疾病。与同期诊断出的结核分枝杆菌疾病病例相比,发病率为0.9%。患者的平均年龄为32岁(范围为5至68岁)。5例(50%)患者出现肺部疾病,2例出现淋巴结炎,2例出现胸腔积液,1例出现腹膜炎。最显著的流行病学特征是有2名患者是兽医专业学生。有1例因卵巢肿瘤伴腹腔播散死亡。其他病例对6至12个月的标准化疗反应良好,所有患者均治愈且无复发。