在中非共和国洛巴耶的一个俾格米人群中，用苄星青霉素治疗皮肤雅司病病变后的临床结果。
Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic.
作者信息
Manirakiza Alexandre, Boas Susana Vilas, Beyam Narcisse, Zadanga Germain, Konamna François Xavier, Njuimo Siméon P, Laganier Rémi
机构信息
Institut Pasteur de Bangui, PO Box 923, Bangui, Central African Republic.
出版信息
BMC Res Notes. 2011 Dec 15;4:543. doi: 10.1186/1756-0500-4-543.
BACKGROUND
Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region.
FINDINGS AND CONCLUSION
The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.
背景
雅司病是一种由 pertenue 苍白密螺旋体引起的皮肤和骨骼细菌性传染病。该病呈地方性流行，在中非共和国的俾格米人中尤为常见。为评估该人群使用苄星青霉素治疗后的临床治愈率，我们在洛巴伊地区对 243 名患者进行了队列研究。
研究结果与结论
5 个月后皮损愈合率为 95.9%。这一相对令人满意的治疗反应水平表明，雅司病在中非共和国是可以得到控制的。因此，建议加强对新病例和接触者的管理。
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