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[从实验室到自行车。心血管疾病一级和二级预防中与体育活动及运动计划相关的风险评估]

[From bench to bicycle. Risk assessment in connection with sports activities and exercise programs in the primary and secondary prevention of cardiovascular diseases].

作者信息

Schulz Olaf, Dürsch Martin

机构信息

Ambulante & Interventionelle Kardiologie Spandau, Berlin, Germany.

出版信息

Herz. 2003 Aug;28(5):359-73. doi: 10.1007/s00059-003-2463-9.

DOI:10.1007/s00059-003-2463-9
PMID:12928735
Abstract

BACKGROUND

Due to encouraging results of studies investigating the effects of physical activity and training on cardiovascular diseases and due to the integration of preventive strategies into disease management programs by public health organizations, it is expected that a larger population, including cardiovascular patients, will increasingly participate in physical activity, fitness programs, and sports. However, a reduction in cardiovascular events and all-cause mortality by regular physical activity is accompanied by an increased mortality during exertion, as yet, there is no satisfactory definition of risk for all cardiovascular diseases and patient groups.

RISK EVALUATION

A cost-effective preparticipation screening has to consider both the low incidence of events resulting from different diseases which requires subtle diagnostics and the intention of granting the larger population simple access to exercise programs and sports. There is a substantial difference in the risk profile for fatal events in athletes and young fitness program participants on the one hand and older (> 35 years) exercising people with a higher incidence of common cardiovascular diseases on the other. Additionally, a potential exercise-induced progression of chronic heart diseases should be excluded. New imaging techniques, laboratory markers, and genetic indicators will hopefully improve the quality of risk assessment.

CONCLUSION

Establishing standards for diagnostics and risk assessment as well as different types of exercise and training programs, all of which need to be transformed into national guidelines, could help to reduce risks without limiting access to physical exercise and therapy. However, an element of risk will remain if rational cost-effectiveness ratios are to be applied.

摘要

背景

由于研究调查体育活动和训练对心血管疾病影响的结果令人鼓舞,且公共卫生组织将预防策略纳入疾病管理项目,预计包括心血管疾病患者在内的更多人群将越来越多地参与体育活动、健身项目和运动。然而,定期体育活动可降低心血管事件和全因死亡率,但运动期间死亡率会增加,目前,对于所有心血管疾病和患者群体的风险尚无令人满意的定义。

风险评估

具有成本效益的参与前筛查必须既考虑到不同疾病导致的事件发生率低(这需要精细的诊断),又要考虑让更多人群能够轻松参与运动项目和运动的意图。一方面,运动员和年轻健身项目参与者发生致命事件的风险状况与另一方面年龄较大(>35岁)且常见心血管疾病发病率较高的运动人群存在很大差异。此外,应排除运动可能导致的慢性心脏病进展。新的成像技术、实验室标志物和基因指标有望提高风险评估的质量。

结论

制定诊断和风险评估标准以及不同类型的运动和训练项目,所有这些都需要转化为国家指南,这有助于降低风险,同时又不限制人们参与体育锻炼和治疗。然而,如果要应用合理的成本效益比,风险因素仍将存在。

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