Sheth A R, Moodbidri S B, Garde S V, Vanage G R
Institute for Research in Reproduction (ICMR), Bombay, India.
Indian J Exp Biol. 1992 Nov;30(11):1012-6.
Passive immunization of adult rats, hamsters and marmosets with rabbit anti-seminal inhibin resulted in complete or partial block of fertility. The antiserum treatment presumably neutralized endogenous inhibin resulting in an unopposed rise in circulating FSH. This probably led to a refractoriness of the testes to FSH resulting in complete spermatogenic arrest. Nevertheless, there was no change in the mating behaviour of the animals. The antibodies also affected the epididymal spermatozoa by causing large scale agglutination.
用兔抗精液抑制素对成年大鼠、仓鼠和狨猴进行被动免疫，导致生育能力完全或部分受阻。抗血清处理可能中和了内源性抑制素，导致循环中的促卵泡激素（FSH）不受抑制地升高。这可能导致睾丸对FSH产生不应性，从而导致生精完全停滞。然而，动物的交配行为没有变化。这些抗体还通过引起大规模凝集影响附睾精子。
