Rogachefsky Arlene S, Hussain Mussarat, Goldberg David J
Skin Laser and Surgery Specialists of New York and New Jersey, 20 Prospect Avenue, Suite 702, Hackensack, NJ 07601, USA.
Dermatol Surg. 2003 Sep;29(9):904-8. doi: 10.1046/j.1524-4725.2003.29256.x.
Acne scar correction remains a challenge to the dermatologic surgeon. With nonablative laser resurfacing, this correction is imputed to dermal collagen remodeling and acne scar reorganization. Although atrophic acne scars tend to respond to laser treatment, the deeper ice pick and boxcar scars tend to be laser resistant.
To investigate the treatment of atrophic and a mixed pattern of facial acne scars, we evaluated a 1320-nm Nd:YAG laser. Twelve subjects with atrophic facial acne scars (N=6) or a combination of atrophic and pitted, sclerotic, or boxcar scars (N=6) received three laser treatments. Physician and patient acne scar ratings were performed at baseline and at 6 months after the last treatment. Acne scars were rated with a 10-point severity scale.
Mean acne scar improvement was 1.5 points on physician assessments (P=0.002) and 2.2 points on patient assessments (P=0.01). Acne scars were rated more severely by patients than by the physician at all intervals. There were no noted complications at 6 months.
The 1320-nm Nd:YAG laser is a safe and effective nonablative modality for the improvement of atrophic and a mixed pattern of facial acne scars.
痤疮瘢痕的修复仍是皮肤科医生面临的一项挑战。对于非剥脱性激光换肤术而言,这种修复归因于真皮胶原重塑和痤疮瘢痕重组。尽管萎缩性痤疮瘢痕往往对激光治疗有反应,但较深的冰锥样瘢痕和箱车型瘢痕往往对激光治疗有抵抗性。
为了研究萎缩性面部痤疮瘢痕及混合性面部痤疮瘢痕的治疗方法,我们评估了一种1320nm的Nd:YAG激光。12名患有萎缩性面部痤疮瘢痕(n = 6)或萎缩性与凹陷性、硬化性或箱车型瘢痕混合的患者(n = 6)接受了三次激光治疗。在基线期和最后一次治疗后6个月进行医生和患者对痤疮瘢痕的评分。痤疮瘢痕采用10分制严重程度量表进行评分。
医生评估的痤疮瘢痕平均改善程度为1.5分(P = 0.002),患者评估为2.2分(P = 0.01)。在所有时间点,患者对痤疮瘢痕的评分均比医生更为严重。6个月时未发现明显并发症。
1320nm的Nd:YAG激光是一种安全有效的非剥脱性治疗方法,可改善萎缩性及混合性面部痤疮瘢痕。