Chamberlain Alexander J, Walker Neil P J
Department of Dermatology, The Churchill, Oxford Radcliffe Hospitals, Old Road, Headington, Oxford OX3 7LJ, United Kingdom.
Dermatol Surg. 2003 Sep;29(9):968-70. doi: 10.1046/j.1524-4725.2003.29261.x.
There are few satisfactory medical or surgical therapies for cutaneous calcinosis in connective tissue disorders.
Carbon dioxide laser vaporization allows precise ablation of superficial dystrophic calcification. This treatment modality was considered because of the severity of our patient's symptoms and failure to respond to various medical therapies.
Over a 5-year period, six affected digits received a single treatment with carbon dioxide laser vaporization.
Treated digits healed over a 6-week period and led to a significant remission in symptoms. The average remission time for affected digits to date is at least 3 years and has allowed our patient to remain in full-time employment.
Carbon dioxide laser vaporization may offer effective remission of symptoms in cutaneous calcinosis of CREST syndrome (including cutaneous calcinosis, Raynaud's phenomenon, sclerodactyly, and telangiectasia).
对于结缔组织疾病中的皮肤钙化症,几乎没有令人满意的药物或手术治疗方法。
二氧化碳激光汽化可精确消融浅表性营养不良性钙化。鉴于我们患者症状的严重性以及对各种药物治疗均无反应,故考虑采用这种治疗方式。
在5年期间,对6个受累手指进行了单次二氧化碳激光汽化治疗。
治疗后的手指在6周内愈合,症状明显缓解。迄今为止,受累手指的平均缓解时间至少为3年,使我们的患者能够继续全职工作。
二氧化碳激光汽化可能有效缓解CREST综合征(包括皮肤钙化症、雷诺现象、指端硬化和毛细血管扩张)中的皮肤钙化症症状。