通过双能X线吸收法评估儿童骨密度：用途与陷阱
Bone densitometry in children assessed by dual x ray absorptiometry: uses and pitfalls.
作者信息
Fewtrell M S
机构信息
MRC Childhood Nutrition Research Centre, Institute of Child Health, London, and Great Ormond Street Hospital NHS Trust, London, UK.
出版信息
Arch Dis Child. 2003 Sep;88(9):795-8. doi: 10.1136/adc.88.9.795.
Abstract
The importance of bone growth and mineralisation during childhood for bone health in adult life is increasingly accepted, with both nutritional factors(1) and exercise(2) being recognised as influential for normal skeletal development. The appreciation that infancy and childhood are important periods of life for bone development has led to a need for suitable methods for monitoring bone health, both for research purposes and for clinical monitoring of individuals, and hence to an increasing use of bone densitometry in children. This review discusses the role and potential pitfalls of this technique.
摘要
儿童期骨骼生长和矿化对成年后骨骼健康的重要性日益得到认可，营养因素(1)和运动(2)都被认为对正常骨骼发育有影响。认识到婴儿期和儿童期是骨骼发育的重要生命阶段，这就需要有合适的方法来监测骨骼健康，既用于研究目的，也用于对个体的临床监测，因此骨密度测定在儿童中的应用越来越多。本综述讨论了该技术的作用和潜在缺陷。
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Bone densitometry in children assessed by dual x ray absorptiometry: uses and pitfalls.通过双能X线吸收法评估儿童骨密度：用途与陷阱
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本文引用的文献
1
Glucorticoids and bone: some general remarks and some special observations in pediatric patients.
Calcif Tissue Int. 2002 May;70(5):384-90. doi: 10.1007/s00223-001-0043-0. Epub 2002 Apr 19.
2
Diet and healthy bones.饮食与健康骨骼。
Calcif Tissue Int. 2002 May;70(5):400-4. doi: 10.1007/s00223-001-0047-9. Epub 2002 Apr 19.
3
Comparison of adult and paediatric spine and whole body software for the Lunar dual energy X-ray absorptiometer.用于Lunar双能X线吸收仪的成人及儿童脊柱和全身软件的比较。
Br J Radiol. 1999 Oct;72(862):967-76. doi: 10.1259/bjr.72.862.10673948.
4
Anomalies in dual energy X-ray absorptiometry measurements of total-body bone mineral during weight change using Lunar, Hologic and Norland instruments.使用Lunar、Hologic和Norland仪器在体重变化期间进行全身骨矿物质双能X线吸收测定时的异常情况。
Br J Radiol. 1999 Jul;72(859):661-9. doi: 10.1259/bjr.72.859.10624323.
5
Discrepancies in pediatric bone mineral density reference data: potential for misdiagnosis of osteopenia.儿科骨密度参考数据的差异：骨质减少误诊的可能性。
J Pediatr. 1999 Aug;135(2 Pt 1):182-8. doi: 10.1016/s0022-3476(99)70020-x.
6
A new perspective on the causal influence of soft tissue composition on DXA-measured in vivo bone mineral density.关于软组织成分对双能X线吸收法测量的活体骨矿物质密度因果影响的新观点。
J Bone Miner Res. 1998 Nov;13(11):1739-46. doi: 10.1359/jbmr.1998.13.11.1739.
7
Measured and predicted bone mineral content in healthy boys and girls aged 6-18 years: adjustment for body size and puberty.6至18岁健康男孩和女孩的骨矿物质含量测量值与预测值：根据体型和青春期进行调整
Acta Paediatr. 1998 Mar;87(3):244-9. doi: 10.1080/08035259850157264.
8
Prospective ten-month exercise intervention in premenarcheal girls: positive effects on bone and lean mass.对月经初潮前女孩进行为期十个月的前瞻性运动干预：对骨骼和瘦体重的积极影响。
J Bone Miner Res. 1997 Sep;12(9):1453-62. doi: 10.1359/jbmr.1997.12.9.1453.
9
Whole body bone mineral content in healthy children and adolescents.健康儿童和青少年的全身骨矿物质含量。
Arch Dis Child. 1997 Jan;76(1):9-15. doi: 10.1136/adc.76.1.9.
10
Uncritical use of bone mineral density in absorptiometry may lead to size-related artifacts in the identification of bone mineral determinants.在吸收测定法中不加区分地使用骨矿物质密度可能会在确定骨矿物质决定因素时导致与大小相关的假象。
Am J Clin Nutr. 1994 Dec;60(6):837-42. doi: 10.1093/ajcn/60.6.837.
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