Saunders Jimmy H, van Bree Henri, Gielen Ingrid, de Rooster Hilde
Department of Medical Imaging, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
Vet Radiol Ultrasound. 2003 Jul-Aug;44(4):409-13. doi: 10.1111/j.1740-8261.2003.tb00477.x.
Computed tomographic (CT) studies of 80 dogs with chronic nasal disease (nasal neoplasia (n = 19), nasal aspergillosis (n = 46), nonspecific rhinitis (n = 11), and foreign body rhinitis (n = 4)) were reviewed retrospectively by two independent observers. Each observer filled out a custom-designed list to record his or her interpretation of the CT signs and selected a diagnosis. Accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for the diagnosis of each disease. The agreement between observers was evaluated. The CT signs corresponded to those previously described in the literature. CT had an accuracy greater than 90% for each observer in all disease processes. The sensitivity, specificity, PPV, and NPV were greater than 80% in all dogs with the exception of the PPV of foreign body rhinitis (80% for observer A and 44% for observer B). There was a substantial, to almost perfect, agreement between the two observers regarding the CT signs and diagnosis. This study indicates a high accuracy of CT for diagnosis of dogs with chronic nasal disease. The differentiation between nasal aspergillosis restricted to the nasal passages and foreign body rhinitis may be difficult when the foreign body is not visible.
两名独立观察者对80只患有慢性鼻腔疾病的犬（鼻腔肿瘤（n = 19）、鼻曲霉菌病（n = 46）、非特异性鼻炎（n = 11）和异物性鼻炎（n = 4））的计算机断层扫描（CT）研究进行了回顾性分析。每位观察者填写一份定制的清单，记录其对CT征象的解读并选择一种诊断。计算每种疾病诊断的准确性、敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）。评估观察者之间的一致性。CT征象与文献中先前描述的相符。在所有疾病过程中，每位观察者的CT诊断准确性均超过90%。除异物性鼻炎的PPV外（观察者A为80%，观察者B为44%），所有犬的敏感性、特异性、PPV和NPV均大于80%。两位观察者在CT征象和诊断方面有高度一致，几乎完全相符。本研究表明CT对诊断犬慢性鼻腔疾病具有较高的准确性。当异物不可见时，局限于鼻腔的鼻曲霉菌病与异物性鼻炎可能难以区分。
