囊胚移植与卵裂期移植的性别比例比较。
Comparison of the sex ratio with blastocyst transfer and cleavage stage transfer.
作者信息
Milki Amin A, Jun Sunny H, Hinckley Mary D, Westphal Lynn W, Giudice Linda C, Behr Barry
机构信息
Department of Gynecology and Obstetrics, Stanford University School of Medicine, Stanford, California 94305, USA.
出版信息
J Assist Reprod Genet. 2003 Aug;20(8):323-6. doi: 10.1023/a:1024861624805.
PURPOSE
To evaluate the sex ratio in births conceived with blastocyst transfer compared to day 3-ET.
METHODS
A retrospective analysis of IVF patients who became pregnant after blastocyst or cleavage stage transfer at Stanford University Hospital and a literature review were performed.
RESULT(S): In the day 3-ET group, the male-to-female (M/F) ratio was 157/139 (53%/47%) compared to 97/66 (59.5%/40.5%) in the blastocyst group (P = 0.18). Similar trends have been found in individual studies in the literature but reached statistical significance in only one out of six reports reviewed. The combined data from our study and the literature show a male-to-female ratio of 797/594 (57.3%/42.7%) in blastocyst transfer compared to 977/932 (51.2%/48.8%) in day 3-ET (P = 0.001).
CONCLUSION(S): Although individual studies may lack power to show an altered sex ratio with blastocyst transfer, the combined data presented in this report do suggest that the M/F ratio is higher with blastocyst transfer compared to cleavage stage transfer.
目的
评估与第3天胚胎移植相比，囊胚移植受孕出生的性别比例。
方法
对斯坦福大学医院囊胚或卵裂期移植后怀孕的体外受精患者进行回顾性分析，并进行文献综述。
结果
在第3天胚胎移植组中，男女比例为157/139（53%/47%），而囊胚组为97/66（59.5%/40.5%）（P = 0.18）。文献中的个别研究也发现了类似趋势，但在所审查的六份报告中只有一份达到统计学显著性。我们的研究和文献的综合数据显示，囊胚移植的男女比例为797/594（57.3%/42.7%），而第3天胚胎移植为977/932（51.2%/48.8%）（P = 0.001）。
结论
尽管个别研究可能缺乏显示囊胚移植改变性别比例的效力，但本报告中呈现的综合数据确实表明，与卵裂期移植相比，囊胚移植的男女比例更高。
Zotero 插件