Krutmann J
Institut für Umweltmedizinische Forschung an der Heinrich-Heine-Universität gGmbH, Düsseldorf.
Hautarzt. 2003 Sep;54(9):809-17. doi: 10.1007/s00105-003-0575-5.
The study of the molecular basis of aging is becoming increasingly important for environmental and dermatological research. In addition to ultraviolet radiation, there are other environmental influences which play a significant role in premature aging processes of the human skin. These include tobacco smoke and, according to recent results, also infrared radiation, ozone and other environmental hazards. Based on our current understanding of the molecular biological basis of the effects of environmental hazards, this overview aims at listing the most important findings which contribute to aging of the skin.
衰老的分子基础研究对于环境和皮肤病学研究而言正变得愈发重要。除紫外线辐射外,还有其他环境因素在人类皮肤过早衰老过程中发挥着重要作用。这些因素包括烟草烟雾,而且根据最近的研究结果,还包括红外线辐射、臭氧及其他环境危害。基于我们目前对环境危害影响的分子生物学基础的理解,本综述旨在列出有助于皮肤衰老的最重要研究发现。