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对雅温得(喀麦隆,中非)的志愿者学生进行沙眼衣原体感染筛查及对分离出的沙眼衣原体菌株进行基因分型。

Screening of volunteer students in Yaounde (Cameroon, Central Africa) for Chlamydia trachomatis infection and genotyping of isolated C. trachomatis strains.

作者信息

Ngandjio Antoinette, Clerc Maithe, Fonkoua Marie Christine, Thonnon Jocelyn, Njock Friede, Pouillot Regis, Lunel Françoise, Bebear Christiane, De Barbeyrac Bertille, Bianchi Anne

机构信息

Centre Pasteur du Cameroun, Yaounde, Cameroon. Laboratoire de Bactériologie, Centre National de Référence des Infections à Chlamydia, Université de Bordeaux II, Bordeaux, France.

出版信息

J Clin Microbiol. 2003 Sep;41(9):4404-7. doi: 10.1128/JCM.41.9.4404-4407.2003.

DOI:10.1128/JCM.41.9.4404-4407.2003
PMID:12958277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC193842/
Abstract

The prevalence of Chlamydia trachomatis infection was 3.78% out of 1,277 volunteer students screened by direct fluorescence assay and Cobas Amplicor PCR. The infection was associated with the nonuse or inconsistent use of condoms in women (P = 0.026) and a previous sexually transmitted infection in men (P = 0.023). The most frequent genotypes determined by sequencing the omp1 genes of 25 clinical isolates were E (44%) and F (20%), and some strains harbored mutations, but E genotype strains did not.

摘要

在通过直接荧光检测法和Cobas Amplicor聚合酶链反应对1277名志愿学生进行筛查后,沙眼衣原体感染率为3.78%。女性感染与未使用或不坚持使用避孕套有关(P = 0.026),男性感染与既往性传播感染有关(P = 0.023)。对25株临床分离株的omp1基因进行测序后确定,最常见的基因型为E型(44%)和F型(20%),一些菌株存在突变,但E基因型菌株没有。

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