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本文引用的文献

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A new phage-typing scheme for Salmonella typhi-murium.一种用于鼠伤寒沙门氏菌的新噬菌体分型方案。
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Translocation of integron-associated resistance in a natural system: acquisition of resistance determinants by Inc P and Inc W plasmids from Salmonella enterica Typhimurium DT104.整合子相关抗性在自然系统中的转移：Inc P和Inc W质粒从肠炎沙门氏菌鼠伤寒亚种DT104获得抗性决定子。
Microb Drug Resist. 2002 Fall;8(3):151-60. doi: 10.1089/107662902760326850.
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Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.肠炎沙门氏菌鼠伤寒血清型LT2全基因组序列
Nature. 2001 Oct 25;413(6858):852-6. doi: 10.1038/35101614.
4
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.作为从大肠杆菌中分离出的1类整合子中的一个基因盒的新型链霉素和壮观霉素抗性基因。
Antimicrob Agents Chemother. 1999 Dec;43(12):3036-8. doi: 10.1128/AAC.43.12.3036.
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Harmonization of antibiotic susceptibility testing for Salmonella: results of a study by 18 national reference laboratories within the European Union-funded Enter-net group.沙门氏菌抗生素敏感性试验的协调：欧盟资助的Enter-net小组内18个国家参考实验室的研究结果
Microb Drug Resist. 1999 Fall;5(3):195-200. doi: 10.1089/mdr.1999.5.195.
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Molecular characterization of an antibiotic resistance gene cluster of Salmonella typhimurium DT104.鼠伤寒沙门氏菌DT104抗生素抗性基因簇的分子特征分析
Antimicrob Agents Chemother. 1999 Apr;43(4):846-9. doi: 10.1128/AAC.43.4.846.
7
Molecular epidemiology of antibiotic resistance genes in multiresistant epidemic Salmonella typhimurium DT 104.多重耐药流行鼠伤寒沙门氏菌DT104中抗生素耐药基因的分子流行病学
Microb Drug Resist. 1998 Summer;4(2):113-8. doi: 10.1089/mdr.1998.4.113.
8
Characterisation of integrons and antibiotic resistance genes in Danish multiresistant Salmonella enterica Typhimurium DT104.丹麦多重耐药肠炎沙门氏菌鼠伤寒血清型DT104中整合子及抗生素抗性基因的特征分析
FEMS Microbiol Lett. 1997 Dec 1;157(1):177-81. doi: 10.1111/j.1574-6968.1997.tb12770.x.
9
Rapid pulsed-field gel electrophoresis protocol for typing of Escherichia coli O157:H7 and other gram-negative organisms in 1 day.用于在1天内对大肠杆菌O157:H7及其他革兰氏阴性菌进行分型的快速脉冲场凝胶电泳方案。
J Clin Microbiol. 1997 Nov;35(11):2977-80. doi: 10.1128/jcm.35.11.2977-2980.1997.
10
Quinolone resistance mutations in the gyrA gene of clinical isolates of Salmonella.沙门氏菌临床分离株gyrA基因中的喹诺酮耐药性突变。
Microb Drug Resist. 1996 Fall;2(3):299-302. doi: 10.1089/mdr.1996.2.299.

肠炎沙门氏菌血清型鼠伤寒DT104喹诺酮耐药性的体内演变

In vivo development of quinolone resistance in Salmonella enterica serotype typhimurium DT104.

作者信息

Kristiansen Malthe A Melau, Sandvang Dorthe, Rasmussen Thorkild Bremholm

机构信息

Department of Clinical Microbiology, Research Unit for Clinical Microbiology, University of Southern Denmark, 6400 Sønderborg, Denmark.

出版信息

J Clin Microbiol. 2003 Sep;41(9):4462-4. doi: 10.1128/JCM.41.9.4462-4464.2003.

DOI:10.1128/JCM.41.9.4462-4464.2003
PMID:12958295
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC193822/
Abstract

Salmonella enterica serotype Typhimurium definitive phage type 104 was isolated several times from the same patient over a period of 2 years. The strain developed reduced sensitivity to fluoroquinolones, and a mutation in the gyrA gene that is associated with reduced sensitivity to quinolones was identified.

摘要

肠炎沙门氏菌鼠伤寒血清型104型在两年时间内多次从同一患者身上分离得到。该菌株对氟喹诺酮类药物的敏感性降低，并且鉴定出与对喹诺酮类药物敏感性降低相关的gyrA基因突变。