Siegel M, Skeer M
Boston University School of Public Health, Social and Behavioral Sciences Department, Boston, Massachusetts 02118, USA.
Tob Control. 2003 Sep;12(3):333-8. doi: 10.1136/tc.12.3.333.
To review existing data on exposure to secondhand smoke in bars, bowling alleys, billiard halls, betting establishments, and bingo parlours (the "5 B's") as assessed by ambient nicotine air concentration measurements and to estimate the excess lung cancer mortality risk associated with this exposure.
Using the Medline, Toxline, and Toxnet databases, the internet, and bibliographies of relevant articles, we identified studies that reported measurements of ambient nicotine concentrations in the 5 B's.
Studies were included if they reported a mean concentration of ambient nicotine measured in at least one of the 5 B's.
We calculated a weighted average of nicotine concentrations in each of the 5 B's. We then estimated the working lifetime excess lung cancer mortality risk associated with this exposure, as well as with exposure at the upper and lower limits of the range of mean exposures reported in all of the studies in each establishment category.
Nicotine concentrations in the 5 B's were 2.4 to 18.5 times higher than in offices or residences, and 1.5 to 11.7 times higher than in restaurants. At these exposure levels, estimated working lifetime excess lung cancer mortality risk from secondhand smoke exposure for workers in the 5 B's is between 1.0-4.1/1000, which greatly exceeds the typical de manifestis risk level of 0.3/1000.
Workers in the 5 B's have high levels of occupational exposure to secondhand smoke and must be included in workplace smoking regulations.
通过环境尼古丁空气浓度测量来回顾关于酒吧、保龄球馆、台球厅、博彩场所和宾果游戏厅(“五B场所”)二手烟暴露的现有数据,并估计与此暴露相关的肺癌超额死亡风险。
利用医学在线数据库(Medline)、毒理学在线数据库(Toxline)和毒理学网络数据库(Toxnet)、互联网以及相关文章的参考文献,我们确定了报告五B场所环境尼古丁浓度测量值的研究。
如果研究报告了在至少一个五B场所测量的环境尼古丁平均浓度,则纳入该研究。
我们计算了每个五B场所尼古丁浓度的加权平均值。然后,我们估计了与此暴露相关的工作寿命期间肺癌超额死亡风险,以及与每个场所类别中所有研究报告的平均暴露范围上限和下限暴露相关的风险。
五B场所的尼古丁浓度比办公室或住宅高2.4至18.5倍,比餐馆高1.5至11.7倍。在这些暴露水平下,估计五B场所工作人员因二手烟暴露导致的工作寿命期间肺癌超额死亡风险在1.0 - 4.1/1000之间,这大大超过了典型的明显风险水平0.3/1000。
五B场所的工作人员二手烟职业暴露水平较高,必须将其纳入工作场所吸烟规定。