Jacotot B, Delahaye F
Service de médecine interne V, hôpital Henri-Mondor, Créteil.
Arch Mal Coeur Vaiss. 1992 Oct;85 Spec No 3:83-6.
Many epidemiological and experimental studies have confirmed the continuous positive relationship between serum cholesterol levels and coronary risk. Therapeutic trials have demonstrated that the lowering of serum cholesterol by diet or drugs can lower this coronary risk. The benefits have been shown in men and women, the young and old, in those with a high coronary risk due to raised serum cholesterol and LDL and those with only moderately increased risk. In addition, therapeutic interventions on serum cholesterol are cost-effective. These observations more than justify the present national program of lowering the serum cholesterol.
许多流行病学和实验研究已证实血清胆固醇水平与冠心病风险之间存在持续的正相关关系。治疗试验表明,通过饮食或药物降低血清胆固醇可降低这种冠心病风险。这些益处已在男性和女性、年轻人和老年人中得到证实,无论是因血清胆固醇和低密度脂蛋白升高而具有高冠心病风险的人群,还是风险仅适度增加的人群。此外,针对血清胆固醇的治疗干预具有成本效益。这些观察结果足以证明目前国家降低血清胆固醇计划的合理性。