Serri Omar, Chik Constance L, Ur Ehud, Ezzat Shereen
Division of Endocrinology, University of Montréal, Montréal, Que.
CMAJ. 2003 Sep 16;169(6):575-81.
Prolactin is a pituitary hormone that plays a pivotal role in a variety of reproductive functions. Hyperprolactinemia is a common condition that can result from a number of causes, including medication use and hypothyroidism as well as pituitary disorders. Depending on the cause and consequences of the hyperprolactinemia, selected patients require treatment. The underlying cause, sex, age and reproductive status must be considered. We describe the diagnostic approach and management of hyperprolactinemia in various clinical settings, with emphasis on newer diagnostic strategies and the role of various therapeutic options, including treatment with selective dopamine agonists.
催乳素是一种垂体激素，在多种生殖功能中起关键作用。高催乳素血症是一种常见病症，可由多种原因引起，包括药物使用、甲状腺功能减退以及垂体疾病。根据高催乳素血症的病因和后果，部分患者需要接受治疗。必须考虑潜在病因、性别、年龄和生殖状态。我们描述了在各种临床情况下高催乳素血症的诊断方法和管理，重点介绍了更新的诊断策略以及各种治疗选择的作用，包括使用选择性多巴胺激动剂进行治疗。
