Lazzari R, Collina A, Masi M, Vallini M, Corvaglia L, Bochicchio A
Clinica Pediatrica III, Università di Bologna, Italia.
Pediatr Med Chir. 1992 Nov-Dec;14(6):589-92.
A group of 81 teenage coeliac patients were recently followed to monitor their compliance with a gluten free diet and also to correlate this with: their general wellbeing, height and weight, antigliadin and antiendomisyal antibody levels and jejunal mucosa patterns. Fifty two patients (64.1%) were on a strict gluten free diet; 18 (22.3%) admitted an occasional gluten intake; 11 (13.6%) were on a normal diet. Symptoms were more frequent in non-compliers that in compliers. There was no appreciable difference between the groups in regard to height and body-mass index, but patients on a normal diet were lighter than the others. Small bowel biopsy was performed on 18 patients with various histological findings. Antigliadin antibodies and antiendomysium antibodies were good indications of a patient's gluten free diet compliance and mucosal damage.
最近对一组81名青少年乳糜泻患者进行了跟踪,以监测他们对无麸质饮食的依从性,并将其与以下方面进行关联:他们的总体健康状况、身高和体重、抗麦胶蛋白和抗肌内膜抗体水平以及空肠黏膜模式。52名患者(64.1%)严格遵循无麸质饮食;18名(22.3%)承认偶尔摄入麸质;11名(13.6%)采用正常饮食。不依从者的症状比依从者更频繁。两组在身高和体重指数方面没有明显差异,但采用正常饮食的患者比其他患者体重更轻。对18名有各种组织学结果的患者进行了小肠活检。抗麦胶蛋白抗体和抗肌内膜抗体是患者无麸质饮食依从性和黏膜损伤的良好指标。