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脑内钠钾ATP酶的定位

Localization of Na+, K+-ATPase in brain.

作者信息

Stahl L W, Broderson S H

出版信息

Fed Proc. 1976 May 1;35(6):1260-5.

PMID:131040
Abstract

Enzyme activity, representing the sites of K+-stimulated p-nitrophenylphosphatase, a component of the sodium, potassium-stimulated-adenosinetriphosphatase system, has been localized in the somatosensory cortex of the rat brain. The reaction product is most obviously associated with fibers that are thought to be axons and dendrites. Large dendrite-like fibers appear to arise in layer 5 of the cortex and arborize in layers 1 through 4. Smaller, reactive fibers are found throughout the cortical layers. Neuron cell bodies did not exhibit substantial enzymatic activity. It did not appear that glia contributed significantly to the activity in cerebral cortex.

摘要

代表钾离子刺激的对硝基苯磷酸酶(钠钾刺激的三磷酸腺苷酶系统的一个组成部分)位点的酶活性,已定位在大鼠脑体感皮层中。反应产物最明显地与被认为是轴突和树突的纤维相关。大的树突样纤维似乎起源于皮层第5层,并在第1至4层形成分支。较小的反应性纤维见于整个皮层各层。神经元细胞体未表现出明显的酶活性。似乎神经胶质对大脑皮层的活性没有显著贡献。

相似文献

1
Localization of Na+, K+-ATPase in brain.脑内钠钾ATP酶的定位
Fed Proc. 1976 May 1;35(6):1260-5.
2
Histochemical localization of potassium-stimulated P-nitrophenylphosphatase activity in the somatosensory cortex of the rat.钾刺激的对硝基苯磷酸酶活性在大鼠体感皮层中的组织化学定位。
J Histochem Cytochem. 1976 Jun;24(6):731-9. doi: 10.1177/24.6.181489.
3
[An electron microscopic study of the localization of the activity of the ouabain-sensitive, potassium-dependent p-nitrophenylphosphatase component of the Na, K-ATPase complex in the rat brain].[大鼠脑中钠钾-ATP酶复合物哇巴因敏感、钾依赖对硝基苯磷酸酶成分活性定位的电子显微镜研究]
Tsitologiia. 1990;32(9):868-72.
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REM sleep deprivation-induced noradrenaline stimulates neuronal and inhibits glial Na-K ATPase in rat brain: in vivo and in vitro studies.快速眼动睡眠剥夺诱导的去甲肾上腺素刺激大鼠脑内神经元并抑制神经胶质细胞的钠钾ATP酶:体内和体外研究
Neurochem Int. 2009 Jan;54(1):65-71. doi: 10.1016/j.neuint.2008.10.006. Epub 2008 Nov 1.
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[Study of ADP effect on brain Na+, K+-ATPase].[ADP对脑钠钾ATP酶作用的研究]
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Changes in cation transport and (Na + K)-activated adenosine triphosphatase produced by chronic administration of ethanol.长期给予乙醇所产生的阳离子转运及(钠+钾)激活的三磷酸腺苷酶的变化。
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Fine structural localization of potassium-stimulated rho nitrophenylphosphatase activity in denrites of the cerebral cortex.钾刺激的 rho 硝基苯磷酸酶活性在大脑皮质树突中的精细结构定位。
J Cell Biol. 1978 May;77(2):R13-7. doi: 10.1083/jcb.77.2.r13.
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[Isolation of Na+, K+-ATP-ase].[钠钾-ATP酶的分离]
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Effects of adrenocortical steroids and of adrenocorticotrophic hormone on (Na+-K+)-ATPase in immature cerebral cortex.肾上腺皮质类固醇和促肾上腺皮质激素对未成熟大脑皮质中(钠 - 钾)-ATP 酶的影响。
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[Activity of acetylcholinesterase and also Mg- and (K+Na)-stimulated ATPase in subcellular fractions of rat brain in normal conditions and during administration of triftazine].[正常条件下及三氟拉嗪给药期间大鼠脑亚细胞组分中乙酰胆碱酯酶以及镁离子和(钾离子+钠离子)刺激的ATP酶的活性]
Vopr Med Khim. 1974 Sep-Oct;20(5):528-34.

引用本文的文献

1
Microscopical methods for the localization of Na+,K+-ATPase.Na⁺,K⁺-ATP酶定位的显微镜方法。
Histochem J. 1981 May;13(3):397-418. doi: 10.1007/BF01005056.
2
The effect of physostigmine on (Na+ + K+)-ATPase activity in different rat brain regions.毒扁豆碱对不同大鼠脑区(钠+钾)-ATP酶活性的影响。
Experientia. 1980 Dec 15;36(12):1348-50. doi: 10.1007/BF01960090.
3
[3H]ouabain autoradiography of frog retina.蛙视网膜的[3H]哇巴因放射自显影术。
J Cell Biol. 1980 May;85(2):313-24. doi: 10.1083/jcb.85.2.313.
4
Immunocytochemical localization of NA+, K+-ATPase in primary cultures of rat retina.大鼠视网膜原代培养物中钠钾ATP酶的免疫细胞化学定位
Neurochem Res. 1984 Jun;9(6):757-69. doi: 10.1007/BF00965664.
5
Fine structural localization of potassium-stimulated rho nitrophenylphosphatase activity in denrites of the cerebral cortex.钾刺激的 rho 硝基苯磷酸酶活性在大脑皮质树突中的精细结构定位。
J Cell Biol. 1978 May;77(2):R13-7. doi: 10.1083/jcb.77.2.r13.