阿奇霉素与磺胺嘧啶协同组合用于治疗小鼠弓形虫病
Synergistic combination of azithromycin and sulfadiazine for treatment of toxoplasmosis in mice.
作者信息
Araujo F G, Lin T, Remington J S
机构信息
Research Institute, Palo Alto Medical Foundation, California 94301.
出版信息
Eur J Clin Microbiol Infect Dis. 1992 Jan;11(1):71-3. doi: 10.1007/BF01971278.
PMID:1314177
Abstract
Experiments were performed in vivo in a mouse model of acute toxoplasmosis to evaluate the effectiveness of the combination azithromycin/sulfadiazine. Azithromycin alone or sulfadiazine alone, at doses that did not provide any protection against death due to toxoplasmosis, were remarkably and significantly synergistic against murine toxoplasmosis when administered in combination.
摘要
在急性弓形虫病小鼠模型中进行了体内实验，以评估阿奇霉素/磺胺嘧啶联合用药的有效性。单独使用阿奇霉素或单独使用磺胺嘧啶时，在未提供任何抗弓形虫病致死保护作用的剂量下，联合使用时对小鼠弓形虫病具有显著的协同作用。
Zotero 插件