罗红霉素（RU 965）与干扰素对刚地弓形虫的体内协同作用。
In vivo synergism of roxithromycin (RU 965) and interferon against Toxoplasma gondii.
作者信息
Hofflin J M, Remington J S
出版信息
Antimicrob Agents Chemother. 1987 Feb;31(2):346-8. doi: 10.1128/AAC.31.2.346.
Abstract
We investigated the activity of roxithromycin (RU 965) and gamma interferon alone and in combination in a murine model of toxoplasmic encephalitis. Roxithromycin at a dosage of 35 or 50 mg per mouse per day decreased mortality. Gamma interferon alone significantly prolonged time to death. When combined, the two agents were remarkably synergistic.
摘要
我们在小鼠弓形虫性脑炎模型中研究了罗红霉素（RU 965）和γ干扰素单独及联合使用的活性。每天每只小鼠给予35或50毫克罗红霉素可降低死亡率。单独使用γ干扰素可显著延长死亡时间。两者联合使用时具有显著的协同作用。
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