Lu Y
Changhai Hospital, 2nd Military Medical University, Shanghai.
Zhonghua Yi Xue Za Zhi. 1992 Jan;72(1):14-7, 62.
Quantitative direct gas-liquid chromatography (GLC) was performed on 74 specimens of surgical infections and relevant findings were compared with cultural results. In the present study, significant amounts of multiple volatile fatty acids (VFA) and/or succinate were found as markers of anaerobic infections. At least one of the VFA (propionic, isobutyric, butyric, isovaleric or valeric acid) greater than or equal to 0.1 mumol/ml and/or succinate greater than or equal to 0.3 mumol/ml was strong evidence for anaerobic infections. More than 3.5 mumol/ml of butyric acid was interpreted as indication of the presence of Fusobacterium spp. Succinate greater than or equal to 0.3 mumol/ml was associated with the presence of Bacteroides fragilis.
对74份手术感染标本进行了定量直接气液色谱法（GLC）检测，并将相关结果与培养结果进行了比较。在本研究中，发现大量多种挥发性脂肪酸（VFA）和/或琥珀酸盐可作为厌氧菌感染的标志物。至少一种VFA（丙酸、异丁酸、丁酸、异戊酸或戊酸）大于或等于0.1μmol/ml和/或琥珀酸盐大于或等于0.3μmol/ml是厌氧菌感染的有力证据。丁酸含量超过3.5μmol/ml被解释为存在梭杆菌属的指示。琥珀酸盐大于或等于0.3μmol/ml与脆弱拟杆菌的存在有关。
