Golino A, Duncan J M, Zeluff B, DePriest J, McAllister H A, Radovancevic B, Frazier O H
Department of Cardiovascular Surgery, Texas Heart Institute, Houston 77225-0345.
J Heart Lung Transplant. 1992 Jul-Aug;11(4 Pt 1):820-3.
Infection is a well-recognized complication of immunosuppressive therapy. We describe a case of leishmaniasis in a 62-year-old man who was undergoing immunosuppressive therapy because of heart transplantation. A geologist and native Texan, the patient had traveled extensively in south-central Texas, but not outside of the continental United States. Cutaneous lesions of the extremities developed, which were diagnosed histologically as leishmaniasis and confirmed by means of transmission electron microscopy. Cultures grew Leishmania mexicana. Treatment with sodium antimony gluconate was successful in healing the infective lesions.
感染是免疫抑制治疗中一种广为人知的并发症。我们描述了一例62岁男性的利什曼病病例，该患者因心脏移植正在接受免疫抑制治疗。这位地质学家是德克萨斯州本地人，曾在德克萨斯州中南部广泛旅行，但未出过美国本土。患者四肢出现皮肤病变，经组织学诊断为利什曼病，并通过透射电子显微镜检查得以确诊。培养物中生长出墨西哥利什曼原虫。使用葡萄糖酸锑钠治疗成功治愈了感染性病变。
