[The functional activity of the thrombocytes in chronic diseases of the large intestine].

Chronic diseases of the large intestine--catarrhal colitis, colonic stasis, unspecific ulcerative colitis, and amebiasis of the large intestine are attended by marked changes in the functional activity of blood platelets and factors of its regulation. They reflect the dynamics of the disease before and after operative and nonoperative treatment. A recurrence of the disease is linked with activation of blood platelets. Trental and contrycal are used for correction of the disorders, which improves the condition of some of the patients. The authors discuss the importance of biogenic amines, cAMP, and functional activity of the blood platelets as universal mechanisms of the development of chronic diseases of the large intestine.