Squarcione S, Germinario C, Iandolo E, Lo Caputo S, Bergamini F, Profeta M L, Greco D, Quarto M, Barbuti S
Institute of Hygiene, University of Bari, Italy.
Vaccine. 1992;10(12):853-6. doi: 10.1016/0264-410x(92)90049-p.
The immunity against poliomyelitis in a representative sample of the Albanian population recently immigrant to Italy was evaluated. A significant number of the subjects examined lacked protective antibodies against one or more polioviruses. The most prevalent seronegativity related to poliovirus type 3 (41.3%), followed by poliovirus type 1 (21.5%). This result was more consistent in the younger age groups. Our data suggest the hypothesis that this problem arises from the use of a vaccine of discontinuous efficacy caused by defective preservation. A poliovaccine booster dose for all emigree subjects aged less than 15 years is suggested.
对最近移民到意大利的阿尔巴尼亚人群的代表性样本进行了脊髓灰质炎免疫评估。在接受检查的受试者中，有相当数量的人缺乏针对一种或多种脊髓灰质炎病毒的保护性抗体。最普遍的血清阴性与3型脊髓灰质炎病毒有关（41.3%），其次是1型脊髓灰质炎病毒（21.5%）。这一结果在较年轻的年龄组中更为一致。我们的数据提出了这样一种假设，即这个问题源于使用了因保存不当而效力不连续的疫苗。建议对所有年龄小于15岁的移民受试者接种一剂脊髓灰质炎疫苗加强针。
