Mizutani K, Inouye S, Hondo R, Akiguchi I, Kimura J
Department of Neurology, Faculty of Medicine, Kyoto University.
Rinsho Shinkeigaku. 1992 May;32(5):532-4.
A case of a 55-year-old male with herpes simplex encephalitis (HSE) was reported. He was admitted because of fever, headache and memory disturbance. T1 weighted MRI showed low signal intensity and T2 weighted imaging revealed high signal intensity in the medial portions of bilateral temporal lobes. Herpes simplex virus (HSV) antibody titer in cerebrospinal fluid (CSF) was not elevated. HSV DNA in CSF was amplified by polymerase chain reaction (PCR) and identified by the microplate hybridization method. The PCR technique would be useful for the diagnosis of HSE.
报告了一例55岁男性单纯疱疹病毒性脑炎（HSE）病例。他因发热、头痛和记忆障碍入院。T1加权磁共振成像（MRI）显示双侧颞叶内侧部分信号强度降低，T2加权成像显示信号强度增高。脑脊液（CSF）中单纯疱疹病毒（HSV）抗体滴度未升高。通过聚合酶链反应（PCR）扩增CSF中的HSV DNA，并采用微孔板杂交法进行鉴定。PCR技术对HSE的诊断有帮助。
