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[上丘激活对印防己毒素诱导点燃过程中惊厥活动的影响]

[The effect of activation of the superior colliculus on the convulsive activity during picrotoxin-induced kindling].

作者信息

Shandra A A, Godlevskiĭ L S, Vikhrestiuk S L, Oleĭnik A A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1992 Jul;78(7):27-33.

PMID:1335894
Abstract

Bilateral administration of picrotoxin, bicucullin or benzilpenicillin to the colliculi superior induced high-amplitude hypersynchronous discharges in rats. In these conditions, a suppression of generalized seizures induced with picrotoxin, was observed. The superior colliculi seem to play a significant part in antiepileptic system, the part being realized through generator mechanism.

摘要

向大鼠双侧上丘注射印防己毒素、荷包牡丹碱或青霉素G钾可诱导出高振幅超同步放电。在这些情况下，可观察到对印防己毒素诱发的全身性癫痫发作的抑制作用。上丘似乎在抗癫痫系统中起重要作用，该作用是通过发生器机制实现的。

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Fiziol Zh SSSR Im I M Sechenova. 1992 Jul;78(7):27-33.
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The influence of activation of the superior colliculi on convulsive activity during picrotoxin kindling.在印防己毒素点燃过程中，上丘激活对惊厥活动的影响。
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