在类风湿性滑膜巨噬细胞中寻找抗原。
Search for antigen in rheumatoid synovial macrophages.
作者信息
Runge L A
出版信息
Ann Rheum Dis. 1976 Apr;35(2):133-7. doi: 10.1136/ard.35.2.133.
Abstract
Peripheral blood monocytes and synovial macrophages obtained from 21 patients with rheumatoid arthritis and from 13 controls were cultured with autologous peripheral blood lymphocytes and stimulation measured by thymidine uptake. Rheumatoid macrophages and monocytes induced a small but significant degree of lymphocyte transformation, and those from the controls did not. The degree of stimulation appears to be more consistent with the nonspecific effect of lymphocyte activating factor, rather than with the presence of a specific synovial antigen.
摘要
从21例类风湿性关节炎患者和13例对照者身上获取外周血单核细胞和滑膜巨噬细胞，将其与自体外周血淋巴细胞一起培养，并通过胸腺嘧啶核苷摄取来测定刺激情况。类风湿性巨噬细胞和单核细胞诱导了小但显著程度的淋巴细胞转化，而对照者的巨噬细胞和单核细胞则没有。刺激程度似乎更符合淋巴细胞激活因子的非特异性作用，而不是存在特异性滑膜抗原。
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本文引用的文献
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