Broor S, Kishore J, Dogra V, Satapathy G, Seth P
Department of Microbiology, All India Institute of Medical Sciences, New Delhi.
Indian J Med Res. 1992 Nov;95:253-5.
An epidemic of acute haemorrhagic conjunctivitis (AHC) caused by a variant of coxsackie A24 (cox A24) occurred in Delhi during August to September 1988. Cox A24 antigen was detected by indirect immunofluorescence (IFA) in conjunctival cell smears of 13 of the 38 (34.2%) patients studied. Virus was isolated from conjunctival swabs in 11 (28.9%) patients and all isolates were neutralized by cox A24 antiserum. Five virus strains sent to Virology Division of Centres for Disease Control, Atlanta, USA, were confirmed as cox A24 variant. Enterovirus type 70 (EV70) was not demonstrable either by IFA or neutralization tests. Conjunctival swabs from 10 healthy laboratory controls did not show any evidence of EV70 or cox A24 virus or their antigens.
1988年8月至9月期间，德里发生了由柯萨奇A24变种（柯萨奇A24）引起的急性出血性结膜炎（AHC）疫情。在所研究的38例患者中，有13例（34.2%）的结膜细胞涂片通过间接免疫荧光法（IFA）检测到柯萨奇A24抗原。11例（28.9%）患者的结膜拭子中分离出病毒，所有分离株均被柯萨奇A24抗血清中和。送往美国亚特兰大疾病控制中心病毒学部门的5株病毒株被确认为柯萨奇A24变种。通过IFA或中和试验均未检测到肠道病毒70型（EV70）。10名健康实验室对照的结膜拭子未显示任何EV70或柯萨奇A24病毒及其抗原的证据。
