Ikeda K, Haga C, Akiyama H, Kase K, Iritani S
Tokyo Institute of Psychiatry, Japan.
Neurosci Lett. 1992 Dec 14;148(1-2):126-8. doi: 10.1016/0304-3940(92)90820-w.
Ultrastructural examination of ghost tangles in an autopsy case of long-term Alzheimer's disease revealed, in addition to degenerate neurites containing paired helical filaments (PHF), astrocytic processes which included PHF. This finding suggests either that astrocytes in ghost tangles possess the capacity to produce PHF or that PHF are incorporated into astrocytes by endocytosis.
在一例长期阿尔茨海默病尸检病例中，对鬼影缠结进行的超微结构检查发现，除了含有双螺旋丝（PHF）的变性神经突外，还发现了含有PHF的星形胶质细胞突起。这一发现表明，要么鬼影缠结中的星形胶质细胞具有产生PHF的能力，要么PHF通过内吞作用被星形胶质细胞摄取。
