Phocas I, Sarandakou A, Kassanos D, Rizos D, Tserkezis G, Koutsikos D
2nd Department of Obstetrics and Gynaecology, University of Athens, Aretaieion University Hospital, Greece.
Int J Gynaecol Obstet. 1992 Jan;37(1):19-28. doi: 10.1016/0020-7292(92)90973-m.
The cycles of 11 renal transplant recipients (RTR), at least 24 months after stabilization of graft function and four hemodialyzed (HD) patients, menstruating regularly, were evaluated by concurrent and systematic determinations throughout the cycle of LH, FSH, estradiol, progesterone, testosterone, prolactin and SHBG and in the case of RTR also by ultrasound follow-up. Biphasic estradiol secretion, midcycle LH and FSH surge, duration of luteal phase, midluteal progesterone values and in the case of RTR, ultrasonic parameters were consistent with: (1) normal ovulatory cycles in five RTR; (2) ovulatory cycles with luteal phase deficiency in five RTR and two HD patients; (3) anovulatory cycles in one RTR and two HD patients. Thus, in HD patients only abnormal cycles of central etiology were found, while in RTR, luteal phase deficiency was a very common syndrome, in equal percentage with normal ovulatory cycles.
对11名肾移植受者（RTR）（移植肾功能稳定至少24个月后）和4名规律月经的血液透析（HD）患者的月经周期进行了评估，在整个周期中同时系统地测定促黄体生成素（LH）、促卵泡生成素（FSH）、雌二醇、孕酮、睾酮、催乳素和性激素结合球蛋白（SHBG），对于肾移植受者还进行了超声随访。双相雌二醇分泌、周期中期LH和FSH峰、黄体期持续时间、黄体中期孕酮值以及对于肾移植受者而言的超声参数与以下情况一致：（1）5名肾移植受者有正常排卵周期；（2）5名肾移植受者和2名血液透析患者有黄体期缺陷的排卵周期；（3）1名肾移植受者和2名血液透析患者有无排卵周期。因此，在血液透析患者中仅发现中枢病因的异常周期，而在肾移植受者中，黄体期缺陷是一种非常常见的综合征，与正常排卵周期的比例相同。
