Wass V J, Wass J A, Rees L, Edwards C R, Ogg C S
Proc Eur Dial Transplant Assoc. 1978;15:178-86.
Sequential changes in luteinising hormone (LH), follicle stimulating hormone (FSH), oestradiol (E2), progesterone (PROG), prolactin (PRL) and testosterone (T) were studied throughout the menstrual cycle in ten women on regular haemodialysis. At the time of study seven women were menstruating and three had secondary amenorrhoea. Only one patient had regular menses. In none of the 15 cycles studied was there a normal luteal phase with an adequate PROG rise, although 9 cycles (4 patients) had E2 changes suggesting that ovulation may have occurred. Increased PRL and T levels were found in 9 and 6 women respectively. These hormonal abnormalities can be related to the menstrual disturbances and explain the low fertility seen in these patients. Bromocriptine or prednisolone may prove useful in their treatment.
对10名定期进行血液透析的女性整个月经周期中促黄体生成素（LH）、促卵泡生成素（FSH）、雌二醇（E2）、孕酮（PROG）、催乳素（PRL）和睾酮（T）的序贯变化进行了研究。研究时，7名女性正在月经，3名继发性闭经。只有1名患者月经规律。在研究的15个周期中，尽管有9个周期（4名患者）的E2变化提示可能发生了排卵，但均未出现黄体期正常且PROG有适当升高的情况。分别在9名和6名女性中发现PRL和T水平升高。这些激素异常可能与月经紊乱有关，并解释了这些患者生育力低下的原因。溴隐亭或泼尼松龙可能对其治疗有用。
