从牛脾脏中分离出的抑素的化学特性。
Chemical characteristics of chalones isolated from bovine spleen.
作者信息
Grundboeck-Juśko J
出版信息
Acta Biochim Pol. 1976;23(2-3):165-70.
PMID:135458
Abstract
Isolation of spleen chalones from the postmicrosomal supernatant is described. Two glycoprotein fractions homogeneous on polyacrylamide-gel electrophoresis were obtained. In the biological test on mice, the preparation of 38 000 mol. wt. inhibited mitosis in spleen cells, and the low-molecular fraction (2100 mol. wt.) in thymus cells, showing respectively the properties of chalones B and T.
摘要
本文描述了从微粒体后上清液中分离脾脏抑素的方法。获得了在聚丙烯酰胺凝胶电泳上均一的两个糖蛋白组分。在对小鼠的生物学试验中，分子量为38000的制剂抑制脾细胞的有丝分裂，而低分子组分（分子量为2100）抑制胸腺细胞的有丝分裂，分别显示出抑素B和T的特性。
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