[镇静剂对大鼠大脑生物电活动的影响]
[Effects of tranquilizing agents on bioelectrical activity of the rat brain].
作者信息
Krapivin S V, Khafiz'ianova R Kh
出版信息
Biull Eksp Biol Med. 1992 Jun;113(6):567-70.
The action of diazepam, meprobamate, trioxazine and mexidol on bioelectrical activity of sensorimotor cortex and dorsal hippocamp of the left and right hemisphere of the brain in conscious rat in free behavior has been studied. All the drugs produced a decline in the frequency of the dominant peak of EEG power spectra. Diazepam and meprobamate increased beta-activity. It is concluded that the decreased frequency may be due to an anxiolytic effect of the tranquilizers, whereas high beta-activity is related to muscle relaxant effect of some drugs.
研究了地西泮、甲丙氨酯、三恶嗪和美西多宁对自由行为的清醒大鼠左右脑半球感觉运动皮层和背侧海马生物电活动的影响。所有药物均使脑电图功率谱主峰频率下降。地西泮和甲丙氨酯增加了β波活动。得出的结论是，频率降低可能是由于镇静剂的抗焦虑作用，而高β波活动与某些药物的肌肉松弛作用有关。
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