Coleman J E, Watson A R
Paediatric Renal Unit, City Hospital, Nottingham, UK.
Adv Perit Dial. 1992;8:396-401.
Data on the micronutrient (vitamin and trace mineral) requirements of children on chronic peritoneal dialysis is limited. Few preparations are of suitable content and palatability. In a prospective study we have assessed and compared the serum levels and dietary intakes of micronutrients (vitamins A, E, B12, folate and zinc, copper, iron) in 7 children on CCPD who were receiving either Ketovite tablets (vitamins C, E and B complex) and Cholecalciferol or a more comprehensive supplement, Paediatric Renal Seravit (vitamins A, E, D, C and B complex with trace minerals). All children received nutritional supplements orally or via a gastrostomy button. These supplements contributed significantly to their nutritional intakes. The mean dietary intakes of the studied micronutrients, with the exception of vitamins A, E, B12 and folate, were below RDA (USA) values. The Renal Seravit was tolerated by only 5 of the 7 patients. There was no significant difference in serum levels of the micronutrients while on the Paediatric Renal Seravit compared to Ketovite. Serum iron levels remained low on both supplements. A comprehensive micronutrient supplement may still be required in children on prolonged dialysis.
关于长期进行腹膜透析的儿童的微量营养素（维生素和微量矿物质）需求的数据有限。很少有制剂的含量和适口性合适。在一项前瞻性研究中，我们评估并比较了7名持续循环腹膜透析（CCPD）儿童的血清水平和微量营养素（维生素A、E、B12、叶酸以及锌、铜、铁）的饮食摄入量，这些儿童要么服用酮维他片（维生素C、E和复合维生素B）和胆钙化醇，要么服用更全面的补充剂——小儿肾用塞拉维他（含维生素A、E、D、C和复合维生素B以及微量矿物质）。所有儿童均通过口服或经胃造口纽扣接受营养补充剂。这些补充剂对他们的营养摄入有显著贡献。除维生素A、E、B12和叶酸外，所研究的微量营养素的平均饮食摄入量均低于美国推荐膳食摄入量（RDA）值。7名患者中只有5名能耐受肾用塞拉维他。与酮维他相比，服用小儿肾用塞拉维他时微量营养素的血清水平没有显著差异。两种补充剂下血清铁水平均保持较低。长期透析的儿童可能仍需要全面的微量营养素补充剂。
