Barnes T R, Halstead S M, Little P W
Charing Cross and Westminster Medical School, London.
Br J Psychiatry. 1992 Dec;161:791-6. doi: 10.1192/bjp.161.6.791.
Iron status and akathisia were assessed in 105 long-stay in-patients who fulfilled DSM-III-R criteria for schizophrenia, all but three of whom were receiving antipsychotic medication. Chronic akathisia was diagnosed in 23% and pseudoakathisia in 20%. No significant correlation was found between serum iron concentration and the severity of akathisia. There was no significant difference in serum iron concentration between patients with chronic akathisia and those without. However, serum iron and percentage saturation were significantly raised in patients with pseudoakathisia compared with patients with chronic akathisia, and tended to be higher than in patients with akathisia. These findings do not support an association between low serum iron and chronic akathisia.
对105名符合精神分裂症DSM-III-R标准的长期住院患者进行了铁状态和静坐不能评估，其中除3人外均接受抗精神病药物治疗。23%的患者被诊断为慢性静坐不能，20%为假性静坐不能。血清铁浓度与静坐不能的严重程度之间未发现显著相关性。慢性静坐不能患者与无慢性静坐不能患者的血清铁浓度无显著差异。然而，与慢性静坐不能患者相比，假性静坐不能患者的血清铁和饱和度百分比显著升高，且往往高于有静坐不能症状的患者。这些发现不支持低血清铁与慢性静坐不能之间存在关联。
