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液相色谱法对合成代谢化合物的纯化与检测

Liquid chromatographic purification and detection of anabolic compounds.

作者信息

van Ginkel L A, Jansen E H, Stephany R W, Zoontjes P W, Schwillens P L, van Rossum H J, Visser T

机构信息

Laboratory for Residue Analysis, National Institute of Public Health and Environmental Protection, Bilthoven, Netherlands.

出版信息

J Chromatogr. 1992 Oct 30;624(1-2):389-401. doi: 10.1016/0021-9673(92)85690-u.

DOI:10.1016/0021-9673(92)85690-u
PMID:1362964
Abstract

The role of liquid chromatography within methods of analysis for steroids, related compounds and beta-agonists in biological samples is discussed. Special attention is given to the application of liquid chromatography in sample preparation and extract clean-up. Different forms of liquid chromatography, including immunoaffinity chromatography, are compared and evaluated. Methods for confirmation based on gas chromatography-mass spectrometry and cryotrapping Fourier transform infrared spectrometry are discussed.

摘要

讨论了液相色谱在生物样品中类固醇、相关化合物和β-激动剂分析方法中的作用。特别关注液相色谱在样品制备和提取物净化中的应用。比较并评估了不同形式的液相色谱,包括免疫亲和色谱。讨论了基于气相色谱-质谱联用和低温捕集傅里叶变换红外光谱法的确证方法。

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Analysis of illegally distributed anabolic steroid products by liquid chromatography with identity confirmation by mass spectrometry or infrared spectrophotometry.通过液相色谱法对非法分销的合成代谢类固醇产品进行分析,并采用质谱法或红外分光光度法进行身份确认。
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Liquid chromatographic and spectral analysis of the 17-hydroxy anabolic steroids.17-羟基合成代谢类固醇的液相色谱和光谱分析
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