Bianchi-Santamaria A, Fedeli S, Santamaria L
Camillo Golgi Institute of General Pathology, Centro Tumori, University of Pavia, Italy.
Med Oncol Tumor Pharmacother. 1992;9(3):151-3. doi: 10.1007/BF02987747.
In a pilot single blind study, beta-carotene (BC) supplementation produced, in ARC patients under current treatment, apparent recovery from asthenia, fever, nocturnal sweating, diarrhoea, loss in weight, and led as a result to an improvement in general health and working efficiency, but not to an improvement in multiple district lympho-adenopathies. Nevertheless, BC appeared to prevent progress to AIDS and, in addition, to lower the effective dosage of AZT used in one case of ARC developed into AIDS, producing a recovery from opportunistic infections and an inhibition of Kaposi sarcoma diffusion, in line with a two-fold rise in CD4 counts.
在一项初步单盲研究中，对接受当前治疗的艾滋病相关综合征（ARC）患者补充β-胡萝卜素（BC）后，患者的乏力、发热、盗汗、腹泻、体重减轻等症状明显恢复，总体健康状况和工作效率也因此得到改善，但多处淋巴结病未见好转。然而，BC似乎可预防病情发展为艾滋病，此外，对于一名发展为艾滋病的ARC患者，BC还降低了所用齐多夫定（AZT）的有效剂量，使机会性感染得以恢复，并抑制了卡波西肉瘤的扩散，同时CD4细胞计数增加了两倍。
