Szybiński Z, Korzeniowska D, Przybyszowski A, Przybyłowski J, Skalski M, Gołkowski F, Stanuch H, Wiśniowski Z
Katedra i Klinika Endokrynologii AM w Krakowie.
Endokrynol Pol. 1991;42(2):263-71.
Epidemiologic studies following the Czernobyl accident were performed in region Kraków, including Kraków, Nowy Sacz and Kielce district. 1426 males and 2495 females were selected according to the random sample on the whole population of Kraków and Nowy Sacz, as well as in some selected areas in Swietokrzyski Mountains, and in Kielcecity. The aim of the study was to assess the results of the prophylaxis with Kalium iodine after the radiation and the incidence of the goiter in the population. It was stated, that 19.2% of the population in Kraków district, 16.9% in Nowy Sacz and 20% in Kielce received the prophylactic dosis of K.J. 80% took mainly the Lugol solution, between May, the 1st and 5th, 1986. Among 18 of person showing side effects like gastrointestinal disturbances, 16 were of female sex. Goiter incidence according to WHO classification was 50.7%, 67.3% and 49.9% in Kraków, Nowy Sacz and Kielce respectively. The difference between the incidence of goiter in males and females was 1:3. In women it was rather Ist and IInd degree of goiter, in men OB and Ist. Nodules of thyroid gland in the rural region of Kraków, Nowy Sacz and Kielce were seen in women in 10.8%, 1.7%, add 12.3% consecutively. Hormonal studies i.e T3, T4, TSH serum concentration showed normal results in all groups studied. TSH concentration was the highest in the group OB. The microsomal and antithyroglobulin antibodies level was the same independently on the prophylactic dosis of Lugol solution. The high incidence of thyroid diseases not related to the accident was observed.(ABSTRACT TRUNCATED AT 250 WORDS)
切尔诺贝利事故后，在克拉科夫地区开展了流行病学研究，该地区包括克拉科夫、新松奇和凯尔采区。根据对克拉科夫和新松奇全体居民以及圣十字山脉某些选定地区和凯尔采市的随机抽样，选取了1426名男性和2495名女性。该研究的目的是评估辐射后服用碘化钾进行预防的效果以及人群中甲状腺肿的发病率。结果表明，克拉科夫区19.2%的人口、新松奇16.9%的人口以及凯尔采20%的人口接受了碘化钾预防剂量。1986年5月1日至5日期间，80%的人主要服用了卢戈氏溶液。在出现胃肠道不适等副作用的18人中，16人为女性。根据世界卫生组织的分类，克拉科夫、新松奇和凯尔采的甲状腺肿发病率分别为50.7%、67.3%和49.9%。男性和女性甲状腺肿发病率的差异为1:3。女性中多为I度和II度甲状腺肿，男性中多为OB度和I度。在克拉科夫、新松奇和凯尔采农村地区，女性甲状腺结节的发生率分别为10.8%、1.7%和12.3%。激素研究，即血清T3、T4、TSH浓度，在所有研究组中均显示正常结果。TSH浓度在OB组中最高。微粒体抗体和抗甲状腺球蛋白抗体水平与卢戈氏溶液的预防剂量无关，保持相同。观察到与事故无关的甲状腺疾病的高发病率。（摘要截取自250字）
